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Photoaged Skin Trial Leyden et al., Cosmetic Dermatology / cited in Pickart 2015 Leyden and colleagues conducted a 12-week, vehicle-controlled trial of topical GHK-Cu cream in 71 women with photoaged facial skin
Can GHK-Cu be used in anti-wrinkle research
The active factor was found to be GHK, with human plasma levels around 200 ng/mL at 20 years of age, declining to less than 60 ng/mL at 60 years of age
Similarly, alcohol metabolism by CYP2E1 enzyme generates reactive oxygen species including hydrogen peroxide (H2O2), superoxide and hydroxyl radicals which have important roles in causing damage to DNA and in fatty acid oxidation
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